Endocrine Abstracts

Much interest has recently focused on the effects in adulthood of an altered in utero environment. We have previously shown that the adult offspring of diabetic rats show reduced urinary calcium output and re-modelling of bone (Hamilton et al 1998, Proc. 3rd Europ. Kidney Res. Forum). Here we tested the hypothesis that changes in renal handling of calcium are the primary in utero effect of diabetes mellitus and are present immediately after birt...